Modern medicine depends on powerful leadership. Some of the doctors are doing research. Some others are running international organizations. They direct the health policy all-over the globe in their capacity as legislatures. They are also responsible for technological innovation. They also are required to mentor the next generation of doctors. Every day, experts question who is the most powerful doctor in the world? The query goes beyond matters of clinical skills to embrace aspects of leadership, influence, and vision, and it also affirms what we hope for-an improvement in health circumstances.